Breast Tumor Diagnosis Using Diode Laser in Near Infrared Region
Abstract
In the last years, new non-invasively laser methods were used to detect breast tumors for pre- and postmenopausal females. The methods based on using laser radiation are safer than the other daily used methods for breast tumor detection like X-ray mammography, CT-scanner, and nuclear medicine.
One of these new methods is called FDPM (Frequency Domain Photon Migration). It is based on the modulation of laser beam by variable frequency sinusoidal waves. The modulated laser radiations illuminate the breast tissue and received from opposite side.
In this paper the amplitude and the phase shift of the received signal were calculated according to the original signal for the sake of diagnosis.
These calculations were carried out for different breast thicknesses to find out the best modulation laser beam wavelength and the optimum breast thickness necessary for diagnosis of benign and malignant tumors.
According to our work the most suitable laser wave length to detect the breast tumor for pre- and postmenopausal females was 956 nm and 674 nm for both malignant and benign tumors.
Downloads
References
[2] Lelia Adelina Paunescu.” Tissue Blood Flow and Oxygen Consumption Measured with Near-Infrared Frequency-Domain Spectroscopy”, Ph.D. thesis Graduate College, the University of Illinois at Urbana-Champaign, 2001.
[3] S. Fantini, S. A. Walker, M. A. Franceschini, M. Kaschke, P. M. Schlag, and K. T. Moesta, ‘‘Assessment of the size, position, and optical properties of breast tumor in vivo by noninvasive optical methods,’’ Appl. Opt. 37, 1982–1989 (1998).
[4] Tromberg, B. J., Coquoz, O., Fishkin, J. B., Pham, T., Anderson, E. R., Butler, J., Cahn, M., Gross, J. D., Venugopalan, V. & Pham, D.” Non-invasive measurements of breast tissue optical properties using frequency-domain photon migration” hilos. Trans. R. Soc. London, B 352, 661–668. 1997.
[5] Ryan Lanning, Bruce Tuomberg. “Non-Invasive Characterization of Breast Cancer Using Near Infrared Optical Spectroscopy”. The UCI Undergraduate Research Journal 2000, pp. 43-50.
[6] Tuan H. Pham, Olivier Coquoz, Joshua B. Fishkin, Eric Anderson, and Bruce J. Tromberg. ”Broad Bandwidth Frequency Domain Instrument for Quantitative Tissue Optical Spectroscopy”. Review of Scientific Instruments, Vol. 71, No. 6, June 2000.
[7] Vladimir Liger, Alexander Zybin, Mikhail Bolshov, and Kay Niemax.”Dual Wavelength Method for Molecular Difference Absorption Measurements in Turbid Media”. Applied Spectroscopy Vol.56, No. 2, 2002, pp. 250-256.
[8] J. B. Fishkin, E. Gratton, M. J. vandeVen, and W. W. Mantulin, ‘‘Diffusion of intensity-modulated near-Infrared light in turbid media,’’ in Time-Resolved Spectroscopy and Imaging of Tissues, B. Chance and A. Katzir, eds., Proc. Soc. Photo-Opt. Instrum. Eng. 1431, 122–135, 1991.
[9] Clare Elwell and Hebden Jem.”Near-Infrared Spectroscopy”. UCL, Biomedical Optical Research Laboratory, January 6, 1999.
[10] Grazia Arpino1, Valerie J Bardou 2, Gary M Clark1 and Richard M Elledge. ”Infiltrating Lobular Carcinoma of the Breast: Tumor Characteristics and Clinical Outcome”. Breast Cancer Research, Vol 6, No 3, 2004.
[11] Breast Net http://www.bci.org.au “Ductal Carcinoma in situ (DCIS), “An information guide for patients. NSW Breast Cancer Institute, 2004.
[12] Joshua B. Fishkin, Peter T. C. So, Albert E. Cerussi, Sergio Fantini,Maria Angela Franceschini, and Enrico Gratton.” Frequency-domain method for measuring spectral properties in multiple-scattering media: methemoglobin absorption spectrum in a tissue like phantom”. Applied Optics, Vol. 34, No. 7, 1 March 1995.
[13] D. Levitz, L. Thrane, M.H. Frosz, P. E. Andersen, C. B. Andersen, J. Valanciunaite, J. Swartling, S. Andersson-Engels, and P. R. Hansen. “Determination of Optical Scattering Properties in Highly-Scattering Media in Optical Coherence Tomography Images”. Opt. Expr. 12, 249-259 (2004).
[14] D. M. Hueber1, M A Franceschini, H Y Ma, Q Zhang J R Ballesteros, S Fantini, D Wallace, V Ntziachristos and B Chance.” Non-invasive and quantitative near-infrared haemoglobin spectrometry in the piglet brain during hypoxic stress, using a frequency-domain multidistance instrument" Phys. Med. Biol. 46 (2001) 41–62. www.iop.org/Journals/pb.
[15] Patterson M. S., Chance B, and Wilson B. C., ‘‘Time Resolved Reflectance and Transmittance for the Noninvasive Measurement of Tissue Optical Properties,’’ Applied. Optics. 28, 2331–2336, (1989).
Downloads
Published
Issue
Section
License
Copyright: Open Access authors retain the copyrights of their papers, and all open access articles are distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided that the original work is properly cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations. While the advice and information in this journal are believed to be true and accurate on the date of its going to press, neither the authors, the editors, nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein.
