Extraction of Penicillin V from Simulated Fermentation Broth by Liquid-Liquid Membrane Technique
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Keywords

Liquid-liquid membrane
Penicillin V
pertraction
extraction

How to Cite

Extraction of Penicillin V from Simulated Fermentation Broth by Liquid-Liquid Membrane Technique. (2012). Al-Khwarizmi Engineering Journal, 8(2), 77-83. https://alkej.uobaghdad.edu.iq/index.php/alkej/article/view/131

Publication Dates

Abstract

Liquid-liquid membrane extraction technique, pertraction, using three types of solvents (methyl isobutyl ketone, n-butyl acetate, and n-amyl acetate) was used for recovery of penicillin V from simulated fermentation broth under various operating conditions of pH value (4-6) for feed and (6-8) for receiver phase, time (0-40 min), and agitation speed (300-500 rpm) in a batch laboratory unit system. The optimum conditions for extraction were at pH of 4 for feed, and 8 for receiver phase, rotation speed of 500 rpm, time of 40 min, and solvent of MIBK as membrane, where more than 98% of penicillin was extracted. 

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